Timeline Negative Three.
In this timeline, women are... different.
Untold ages ago, after Earth was created by The One Above All, he created his children, Humans, to grow, and rule this world, and expand to other lands beyond. But Humanity was a mono-gendered species, made up only of men, and reproducing through mystic rituals that created new life.
This lasted for years, and humanity had grown to rule all of Earth, and was prepared to expand beyond, but they never reached that point.
Sinister rivals of The One saw his new universe, a change from bleak oblivion, and wished to rule this reality themselves. They created the first woman, Pandora, and while she was innocent, and loved by Men, specifically Adam, the chosen leader of Men, she spread the plagues of the dark god Eve to Earth, crippling the human's empire, and sending them into a new dark age, with Women alongside them.
The One saw this, and could not hate Women, as they were innocent puppets, and attempted to adopt them into his world, but he could not separate the plagues from them, and had to watch as his sons and daughters lost their immortality, joining him in his Afterlives, as new humans were born, and eventually, all knowledge and evidence of the old world fell.
Now, humanity is right back where it was before, prepared for a new Space Age, with unique technology only dreamed of in past ages. But the eldritch goddess Eve was not satisfied, in 2016, she subtly controlled many politicians and people as her agents, which would lead to her slow death of humanity. But this plan fell apart, a famous (or infamous) man known as Donald Trump rivaled her takeover of the world superpower of America, and won. With her plans failed, and everything in ruins, she realized the time for subtlety was over.
Many years after the election, though, all have forgotten exactly when, Eve retook her children, absorbing their souls back into her, and turning all women on Earth into her Avatars of Decay.
Earth is in ruins, but humanity lives on. Under the direct protection and guidance of The One, Humanity has been freed of the contaminating Sin, and made flawless, You and many other have unleashed a crusade against Eve and her agents that ravage this world.
TL;DR Holy crusade against the evil THOTS.